Articles
What the research actually says about women's hormonal health and longevity, and what to do about it.
Featured "My brain went from black and white to technicolor."
At an FDA hearing, a patient described what testosterone restoration felt like from the inside. This is the brain science behind why so many women never get tested, and what changes when they do.
"The flatness your antidepressant can't reach."
You can be on an antidepressant that is working and still feel a flatness it cannot touch. For many women that flatness is not depression at all, it is testosterone deficiency on a different brain system.
"She's 57, on testosterone, and building companies with AI."
By around age 40, a woman's testosterone is roughly half what it was in her twenties, the hormone that quietly runs drive and ambition. Here's what getting it back actually looks like, and what it might mean if millions of women did.
Featured "My mother has Alzheimer's. Would estrogen have saved her?"
Some researchers think estrogen protects the aging brain, but only in a narrow window around menopause. My mother was inside that window in 2002. The evidence is still fiercely argued over. What nobody argues about is that she was never even offered the choice.
"What Rachel Rubin told the FDA: what your gynecologist still hasn't heard."
Vaginal estrogen is cheap, barely enters the bloodstream, and cuts UTIs and related mortality. Yet a misplaced black box warning still keeps doctors from prescribing it. Here is the data.
"Before the hot flashes come the years no one warned you about."
Perimenopause is a decade-long transition, and heavy bleeding can be one of its most frightening and least discussed symptoms. Here is what actually happens, and what I wish I had known.
"Why women on (or recently off) birth control can't feel their own libido."
The pill raises SHBG, the protein that binds testosterone, and it can stay elevated for months after you stop. Two women can have identical labs and completely different free hormone levels.
"1 in 5 women on pellets developed this. Were you told?"
Hormone pellets are convenient, but in one published study more than 20 percent of women on them developed endometrial hyperplasia. Here is the science your provider may not have mentioned.
Featured "18,000 to 91,000 women. Who died because of a bad study."
The 2002 WHI announcement set off a mass exodus from hormone therapy. A Yale team later calculated the human cost of that fear, and the peer-reviewed number is staggering.
"I found out I carry two copies of the Alzheimer's gene."
A consumer DNA test reads a tiny fraction of your genome, yet inside that fraction I found my APOE4/4 result. Here is what two copies of the Alzheimer's gene actually mean, and what the test got wrong.
"The $399 test that reads your entire genome."
Whole genome sequencing now costs less than a dental cleaning and reads every base pair, not a fraction. Here is what it actually covers, who owns the data, and what to do with the results.
"My mom has Alzheimer's. Here's the question I can't stop asking."
A review of Estrogen Matters by Dr. Avrum Bluming and Dr. Carol Tavris, and the research it synthesizes about what the 2002 WHI study actually said versus the fear it created.
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